Inhaled Combined Budesonide–Formoterol as Needed in Mild Asthma
نویسندگان
چکیده
منابع مشابه
Regular vs. As-needed inhaled salbutamol in chronic severe asthma
Study objectives: Compare as-needed vs. regular use of an intermediate inhaled dose of salbutamol in chronic severe asthma. Design: This was a 6-week randomized double blind, placebo controlled and crossover study. Patients and interventions: Ten subjects aged 54.9± 3.35 (mean±SEM) yr under inhaled corticosteroid treatment with persistent severe asthma (FEV1= 1.87± 0.27 L; 76.9± 6.7%) received ...
متن کاملDaily Versus As - Needed Inhaled Corticosteroid for Mild Persistent Asthma ( The Helsinki Early Intervention Childhood Asthma Study )
METHODS. The study design was a randomized, doubleblind, placebo-controlled trial, with children assigned randomly to 1 of 3 treatment groups with instructions to treat for 7 days at the onset of each RTI-associated symptom set during a 12-month period: (1) budesonide suspension (1 mg twice daily) plus LTRA placebo, (2) montelukast (4 mg daily) plus ICS placebo, or (3) ICS placebo plus LTRA pla...
متن کاملDaily versus as-needed inhaled corticosteroid for mild persistent asthma (The Helsinki early intervention childhood asthma study)
OBJECTIVE To compare the effect of inhaled budesonide given daily or as-needed on mild persistent childhood asthma. Patients, design and INTERVENTIONS 176 children aged 5-10 years with newly detected asthma were randomly assigned to three treatment groups: (1) continuous budesonide (400 microg twice daily for 1 month, 200 microg twice daily for months 2-6, 100 microg twice daily for months 7-...
متن کاملDaily versus as-needed corticosteroids for mild persistent asthma.
BACKGROUND Although guidelines recommend daily therapy for patients with mild persistent asthma, prescription patterns suggest that most such patients use these so-called controller therapies intermittently. In patients with mild persistent asthma, we evaluated the efficacy of intermittent short-course corticosteroid treatment guided by a symptom-based action plan alone or in addition to daily ...
متن کاملInhaled glucocorticoids promotes osteoporosis in asthma patients
Background: Recently many studies have focused on the possible role of corticosteroids inhalation on osteoporosis in asthma patients. This study aimed to determine whether the indicatives of bone formation or resorption are different between asthma patients with healthy subjects. Materials and Methods: To achieve this outcome, twenty one middle-aged asthma patients treated with inhaled cortico...
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ژورنال
عنوان ژورنال: New England Journal of Medicine
سال: 2018
ISSN: 0028-4793,1533-4406
DOI: 10.1056/nejmoa1715274